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Weight gain would be an expected consequence of antidepressants with affinity for histamine and/or 5-HT 2C receptorsBupropion has no relevant affinity for these receptors and is not associated with weight gainIt is typically associated with a slight weight losse.gapproximately equal to 1.5 kg with initial treatmentIn the long-term relapse prevention studya greater weight loss was observed in patients with a greater body mass index at baseline71.

Adverse Events Occurring at an Incidence of 1or More Among Patients Treated With the Immediate-Release or Sustained-Release Formulations of Bupropion.

FDA pregnancy category CIt is not known whether bupropion will harm an unborn babyTell your doctor if you are pregnant or plan to become pregnant while using this medicine.

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